Friday, June 28, 2013

Drugs Banned In India

The health ministry has suspended the sale of two drugs - painkiller Analgin and anti-diabetes drug Pioglitazone and all its combinations .

While the ban on Analgin in India has come after almost 36 years after the drug was banned in the US (which banned it in 1977), Pioglitazone was pulled out of France in 2011 for an increased risk of bladder cancer.

 This decision comes in the wake of a strong stand by the government on suspending marketing of all drugs prohibited for sale in other countries like the US, the UK, EU and Australia.

The ministry of health and family welfare has suspended the manufacture and sale of all three drugs under Section 26A of the Drugs and Cosmetics Act, 1940 with immediate effect, through a notification issued on June 18, informed sources told TOI. While the ministry has been dilly-dallying on withdrawing analgin and deanxit for years now, despite pressure from a parliamentary panel, the decision on the diabetes drug pioglitazone has taken the industry completely by surprise.

The decision to ban pioglitazone and its combinations will hit the Rs 700-crore market for such drugs and adversely impact a clutch of companies including Abbott, Sun Pharma, USV, Lupin, Ranbaxy and Wockhardt.

Drugs Banned In India



1. Amidopyrine.

 2. Fixed dose combinations of vitamins with anti-inflammatory agents and tranquilizers.

 3. Fixed dose combinations of Atropine in Analgesics and Antipyretics.

 4. Fixed dose combinations of Strychnine and Caffeine in tonics.

 5.Fixed dose combinations of Yohimbine and Strychnine with Testosterone and  Vitamins.

 6. Fixed dose combinations of Iron with Strychnine, Arsenic and Yohimbine.

7. Fixed dose combinations of Sodium Bromide/chloral hydrate with other drugs.

8. Phenacetin.

9. Fixed dose combinations of antihistaminic with anti-diarrhoeals.

          10. Fixed dose combinations of Penicillin with Sulphonamides.

11. Fixed dose combinations of Vitamins with Analgesics.

    B     12.Fixed dose combinations of  any other Tetracycline with Vitamin C. 

    E     13.Fixed dose combinations of Hydroxyquinoline group of drugs with any other drug   except for preparations meant for external use.

  ccc    14. Fixed dose combinations of Corticosteroids with any other drug for internal use.

  ccc    15. Fixed dose combinations of Chloramphenicol with any other drug for internal use.

16.Fixed dose combinations of crude Ergot preparations except those containing Ergotamine, Caffeine, analgesics, antihistamines for the treatment of migraine, headaches.

17.Fixed dose combinations of Vitamins with Anti TB drugs except combination of Isoniazid with Pyridoxine Hydrochloride (Vitamin B6).

18. Penicillin skin/eye Ointment.

19. Tetracycline Liquid Oral preparations.

20. Nialamide.

21. Practolol.

    22. Methapyrilene, its salts.

c    23. Methaqualone.

&   24. Oxytetracycline Liquid Oral preparations.

&   25. Demeclocycline Liquid Oral preparations.

T    26. Combination of anabolic Steroids with other drugs.

cc  27.Fixed dose combination of Oestrogen and Progestin (other than oral contraceptive) containing per tablet estrogen content of more than 50 mcg (equivalent to Ethinyl Estradiol) and progestin content of more than 3 mg (equivalent to Norethisterone Acetate) and all fixed dose combination injectable preparations containing synthetic Oestrogen and Progesterone. (Subs. By Noti. No. 743 (E) dt 10-08-1989)

    28.Fixed dose combination of Sedatives/ hypnotics/anxiolytics with   analgesics-antipyretics.

J    29.Fixed dose combination of Rifampicin, isoniazid and Pyrazinamide, except those which provide daily adult dose given below:

Drugs                             Minimum                 Maximum

Rifampicin                      450 mg                   600 mg

Isoniazid                              300 mg                       400 mg

Pyrazinamide                  1000mg                  1500 mg

   30. Fixed dose combination of Histamine H-2 receptor antagonists with antacids except for those combinations approved by Drugs Controller, India.

   31.The patent and proprietary medicines of fixed dose combinations of essential oils with alcohol having percentage higher than 20% proof except preparations given in the Indian Pharmacopoeia.

   32. All Pharmaceutical preparations containing Chloroform exceeding 0.5% w/w or v/v
   whichever is appropriate.

 33.Fixed dose combination of Ethambutol with INH other than the following: INH
  Ethambutol 200 mg. 600 mg. 300 mg. 800 mg.

      34. Fixed dose combination containing more than one antihistamine.

   B35.Fixed dose combination of any anthelmintic with cathartic/purgative except for

   J 36. Fixed dose combination of Salbutamol or any other drug having primarily bronchodilatory activity with centrally acting anti-tussive and/or antihistamine.

      37.Fixed dose combination of laxatives and/or anti-spasmodic drugs in enzyme preparations.

  G 38.Fixed dose combination of Metoclopramide with systemically absorbed drugs except fixed dose combination of metoclopramide with aspirin/paracetamol

     39.Fixed dose combination of centrally acting, antitussive with antihistamine, having high atropine like activity in expectorants.

     40.Preparations claiming to combat cough associated with asthma containing centrally acting antitussive and/ or an antihistamine.

     41.Liquid oral tonic preparations containing glycerophosphates and/or other phosphates and / or central nervous system stimulant and such preparations containing alcohol more than 20% proof.

     42.Fixed dose combination containing Pectin and/or Kaolin with any drug which is systemically absorbed from GI tract except for combinations of Pectin and/or Kaolin with drugs not systemically absorbed.

   43. Chloral Hydrate as a drug.

    b   44. Dovers Powder I.P.

    b   45. Dover’s Powder Tablets I.P.

    A   46.Antidiarrhoeal formulations containing Kaolin or Pectin or Attapulgite or Activated Charcoal.

    A  47.Antidiarrhoeal formulations containing Phthalyl Sulphathiazole or Sulphaguanidine or Succinyl Sulphathiazole.

    A  48.Antidiarrhoeal formulations containing Neomycin or Streptomycin or Dihydrostreptomycin  including their respective salts or esters.

    A  49.Liquid Oral antidiarrhoeals or any other dosage form for pediatric use containing Diphenoxylate Lorloperamide or Atropine or Belladona including their salts or esters or metabolites Hyoscyamine or their extracts or their alkaloids.

    A  50.Liquid Oral antidiarrhoeals or any other dosage form for pediatric use containing halogenated hydroxyquinolines.

    A  51. Fixed dose combination of antidiarrhoeals with electrolytes.

    C  52. Patent and Proprietary Oral Rehydration Salts other than those conforming to the 

    D  53. Fixed dose combination of Oxyphenbutazone or Phenylbutazone with any other drug.

   H.D54. Fixed dose combination of Analgin with any other drug.

     D 55. Fixed dose combination of dextropropoxyphene with any other drug other than anti-spasmodics and/or non-steriodal anti-inflammatory drugs (NSAIDS).

     D 56. Fixed dose combination of a drug, standards of which are prescribed in the Second Schedule to the said Act with an Ayurvedic, Siddha or Unani drug.

     F 57. Mepacrine Hydrochloride (Quinacrine and its salts) in any dosage form for use for female sterilization or contraception.

     F  58. Fenfluramine and Dexfenfluramine.

     I  59. Fixed dose combination of Diazepam and Diphenhydramine Hydrochloride .

    K  60. Rimonabant.

     L 61 Rosiglitazone

     M 62 Nimesulide formulations for human use in children below 12 years of age.

    M 63. Cisapride and its formulations for human use.

    M 64. Phenylpropanolamine and its formulation for human use.

   M 65. Human Placental Extract and its formulations for human use.

   M 66. Sibutramine and its formulations for human use, and

   M 67. R-Sibutramine and its formulations for human use.

    N 68. Gatifloxacin formulation for systemic use in human by any route including oral and injectable

    N 69. Tegaserod and its formulation for human use.

    The Principal Notification GSR 578 (E) dt.23.7.83.

c    Added b GSR 4(E) dated 31.01.1984

&   Added b GSR 322(E) dated 03.05.1984\

T    Amended by GSR 863(E) dated 22.11.1985

cc   Amended by GSR 743(E) dated 10.08.1989

ccc Amended by GSR 1057(E) dated 03.11.1988

    Added by GSR 999(E) dated 26.12.1990

            Added by GSR 69(E) dated 11.02.1991

       xxx    Added by GSR 304(E) dated 7.06.1990

     @   Added by GSR 444(E) dated 7.06.1992

      b   Added by GSR 111(E) dated 22.02.1994

      A   Added by GSR 731(E) dated 30.09.1994

      B   Added by GSR 848(E) dated 7.12.1994

      C   Added by GSR 57(E) dated 7.02.1995

      D   Added by GSR 633(E) dated 13.09.1995

      E   Added by GSR 793(E) dated 13.03.1995

           Added by GSR 93(E) dated 25.05.1997

      F   Added by GSR 499(E) dated 14.08.1998

      G   Added by GSR 394(E) dated 19.05.1999

      H   Added by GSR 405(E) dated 3.06.1999

      I    Added by GSR 169(E) dated 12.03.2001

      J   Added by GSR 290(E) dated 16.04.2008

       K   Added by GSR 885(E) dated 11.12.2009

        L. Added by GSR 910(E) dated 12.11.2010

    M.  Added by GSR 82(E) dated 10.03.2011

    N.  Added by GSR 218(E) dated 16.03.2011


           1. Nialamide

        2. Practolol

        3. Amidopyrine

        4. Phenacetin

        5. Methapyrilene and its salts

   a   6. Methaqualone

   b   7. Chloral Hydrate as a drug

   c   8. Mepacrine Hydrochloride ( Quinacrine and its Salts) in any dosage form for use for female sterilization or contraception.

        9. Fenfluramine and Dexfenfluramine]

   d   10. Rimonabant


    a  Added by GSR 48(E) dated 31.1.1984

    b  Added by GSR 303(E) dated 7.6.1991

    c  Added by GSR 498(E) dated 14.8.1998

    d Added by GSR 884(E) dated 11.12.2009


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Tuesday, June 4, 2013

Importance of Good Dental Hygiene

Good dental hygiene is very important to our health. It eliminates or reduces bacteria in the mouth that can lead to inflammation that can lead to heart disease and other complications. Luckily you can banish these bad boys by keeping your teeth clean.

Unhealthy bacteria converts sugars from food into lactic acid which creates a sticky layer of plaque on the teeth, destroying tooth enamel and leading to cavities.  For prevention, look for toothpaste that contains cranberry extract and green tea which will keep bacteria from sticking to the teeth. And licorice root and meem to chase away plaque.  And most important diet, limit sticky sugary foods, candies and processed flour foods. Snack on crunchy foods like apples and carrots. They help sweep away food debris, and their high water content and saliva they promote dilutes bacteria.

Bacteria under gums cause inflamed tissue that is prone to bleeding. Floss and picks help dislodge bacteria. B vitamins encourage red blood cell development which is critical for good gum health. Be sure to get plenty of Omega 3 in the diet or take supplements. Eat lots of colorful fruits and vegetables high in vitamins A,C and E, dark leafy greens, tomatoes, carrots, beets, citrus fruits and eggs should do the trick.

Your teeth usually darken as you age, also drinking coffee and tea doesn’t help. You can try whitening toothpastes, whitening pens, mouthwashes, or strips containing hydrogen peroxide, which breaks down in water. They are safe for home use if concentration is no more than 3 percent. Dentists use stronger concentrations. You can also use whitening products like silica, baking powder and bamboo powder.

Bad breath is another factor of bad dental hygiene.  Although, it can be the result of nasal drip, low saliva, acid reflux, or dry mouth. Each creates a low saliva or high acid environment, which causes bacteria to accumulate in sticky, odor causing plaque. Some foods are well known for creating bad breath, such as onions, garlic which produce sulphur compounds responsible for the rotten egg syndrome. Protein rich foods such as cheese, milk and fish create a breeding ground for bacteria,as do acidic drinks like coffee and orange juice.

Eating foods that kill bacteria and keep it from sticking to teeth is an good antidote for bad breath. Green tea, cranberry, and other antioxidants will prevent bad breath. When gums recede from improper brushing or aging, cold and hot foods can cause discomfort. Ease the pain  with products that contain potassium nitrate, or herbs like chamomile, clove oil and myrrh. They have a history of helping pain, inflammation and healing tissue wounds.


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Medicinal Properties of Lovage

Lovage has been used to treat indigestion, arthritis, Bronchitis, painful menstruation and flatulence. It can also be used as a diuretic.
Lovage is a tall perennial plant that is a strong aromatic spice.  It has long been used in cooking, but the seeds, leaves and roots have many medicinal properties and it’s very high in vitamin C.

Lovage has been used to treat indigestion, loss of appetite, stomach and gallbladder insufficiency, feeling of fullness after meals, slow digestion, Rheumatism, arthritis, Bronchitis, gout, cough, problems with urination, kidneys and prostate, sore throats, colic, kidney stones, cystitis, painful menstruation and flatulence.  It has also been used to purify blood, as a diuretic and as a deodorant if added to the bath water.

The Greeks referred to Lovage as Ligustikon.
Lovage was mentioned by the Emperor Charlemagne.  He said that it should be grown in every imperial garden.
Lovage has been used since Greek and Roman times as a seasoning in food, additive to medicines and as an ingredient in love potions.

According to Lovage was dug up at night on Good Friday in order to help ward off either witches or the influence of the Devil.
Lovage has been used for medicinal purposes as early as the 14th Century. It is also known as Ligusticum Levisticum, Old English Lovage, Cornish Lovage, Italian Lovage, Love Persley and Sea Persley.  Lovage should not be taken if pregnant or have kidney disease.


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Monday, June 3, 2013

Health Benefits of Honey

Honey has the ability to boost the immune system, aid in weight loss, reduce the risk of heart disease, relieve indigestion, improve energy levels, relieve sore throats and coughs, clear up acne, slow aging and relieve morning sickness.

Honey is best known as a sweet food that is made by bees using the nectar of flowers, but it has long been used for its abundance of health benefits.  It has been recorded in history as the most used medicine in ancient Egypt. 

Honey has the ability to boost the immune system, aid in weight loss, reduce the risk of heart disease, relieve indigestion, improve energy levels, relieve sore throats and coughs, clear up acne, slow aging and relieve morning sickness.

Honey is best known as a sweet food that is made by bees using the nectar of flowers, but it has long been used for its abundance of health benefits.  It has been recorded in history as the most used medicine in ancient Egypt. 

Bees swallow, digest and regurgitate nectar to make honey.
The honey bee first appeared about 130 million years ago.
Honey bees evolved from short-tongued, spheciform wasps.
According to, In 2700 BC, the first records of the pharmaceutical and nutritional value of honey were found in Mesopotamia, the birthplace of the first organized communities.
The Romans used honey to heal their wounds after battles.
Honey has been used in Ayurvedic medicine in India for at least 4000 years.
Darker honey usually has higher antioxidant levels.  The only health benefits of honey that have been scientifically proven are for wound care and cough suppression, but many continue to stand behind this ancient remedy for almost every illness and ailment there is.


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